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Knockout Cell Lines

Knockout (KO) Cell Lines

CRISPR KO Cell Lines for Precise Gene Editing

Runtogen's CRISPR Knockout Cell Lines are powerful, specially engineered tools for researchers. They enable the exploration of gene function and the advancement of biological research. By selectively disrupting specific genes, these cell lines allow you to study the impact of gene loss on cellular processes, disease models, and drug discovery pathways.

What Are Knockout Cell Lines?

Knockout cell lines are genetically modified cells in which one or more genes have been intentionally "knocked out" or deactivated. Using advanced gene editing technologies like CRISPR-Cas9, we create precise and stable gene disruptions. This allows for a deeper, more accurate understanding of gene function in a controlled setting.

Customizable Knockouts

Tailored to your specific research needs. We can target genes across a wide variety of cell types.

Validated Performance

Each knockout cell line undergoes rigorous quality control and validation to ensure reliable, reproducible results.

Wide Applications

Ideal for functional genomics, disease modeling, drug discovery, and core biomedical research.

Applications of Knockout Cell Lines

Gene Function Research

Knockout cell lines are fundamental for functional genomics. They help you uncover the role of specific genes in cellular processes like growth, differentiation, and metabolism.

Disease Modeling

These cell lines are invaluable for creating accurate in vitro models of diseases, from cancer to neurodegenerative disorders. They allow for better mechanistic understanding and pre-clinical testing of therapeutic strategies.

Drug Discovery & Target Identification

Knockout cell lines are instrumental in high-throughput drug screening. They help researchers identify and validate potential drug targets by assessing compound effects in the absence of a specific gene.

Why Choose Runtogen's KO Cell Lines?

Cutting-edge Technology

We utilize the latest CRISPR-Cas9 gene editing tools to create high-precision knockout cell lines.

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Extensive Ready-Made Library

Save valuable time with immediate access to over 5,000 ready-made, validated knockout cell lines in our catalog.

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Fast Delivery & Expert Support

Get your cell lines quickly and benefit from the support of our specialist team.

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High-Quality Standards

Homozygous clones validated by Sanger sequencing, edited in commonly used cell lines.

Accelerate Your Research

Whether you are studying basic gene function, developing advanced disease models, or screening for new drug targets, our knockout cell lines are engineered to meet the highest standards of quality and precision.

Online Inquiry

  • ARHGAP4 Knockout Cell Line-HCT 116

    ARHGAP4 Knockout Cell Line-HCT 116

    Catalog#: RK-5041
    Size: 1*10^6 cells/vial
    Gene Name: ARHGAP4
  • BMAL1 Knockout Cell Line-HCT 116

    BMAL1 Knockout Cell Line-HCT 116

    Catalog#: RK-5044
    Size: 1*10^6 cells/vial
    Gene Name: BMAL1
  • EDC4 Knockout Cell Line-HCT 116

    EDC4 Knockout Cell Line-HCT 116

    Catalog#: RK-5049
    Size: 1*10^6 cells/vial
    Gene Name: EDC4
  • RNF170 Knockout Cell Line-HCT 116

    RNF170 Knockout Cell Line-HCT 116

    Catalog#: RK-4982
    Size: 1*10^6 cells/vial
    Gene Name: RNF170
  • POLK Knockout Cell Line-HCT 116

    POLK Knockout Cell Line-HCT 116

    Catalog#: RK-4986
    Size: 1*10^6 cells/vial
    Gene Name: POLK
  • CPEB3 Knockout Cell Line-HCT 116

    CPEB3 Knockout Cell Line-HCT 116

    Catalog#: RK-4914
    Size: 1*10^6 cells/vial
    Gene Name: CPEB3
  • LMNB1 Knockout Cell Line-HCT 116

    LMNB1 Knockout Cell Line-HCT 116

    Catalog#: RK-4991
    Size: 1*10^6 cells/vial
    Gene Name: LMNB1
  • PTPRJ Knockout Cell Line-HCT 116

    PTPRJ Knockout Cell Line-HCT 116

    Catalog#: RK-4919
    Size: 1*10^6 cells/vial
    Gene Name: PTPRJ
  • CRY1 Knockout Cell Line-HCT 116

    CRY1 Knockout Cell Line-HCT 116

    Catalog#: RK-4995
    Size: 1*10^6 cells/vial
    Gene Name: CRY1