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Knockout Cell Lines

Knockout (KO) Cell Lines

CRISPR KO Cell Lines for Precise Gene Editing

Runtogen's CRISPR Knockout Cell Lines are powerful, specially engineered tools for researchers. They enable the exploration of gene function and the advancement of biological research. By selectively disrupting specific genes, these cell lines allow you to study the impact of gene loss on cellular processes, disease models, and drug discovery pathways.

What Are Knockout Cell Lines?

Knockout cell lines are genetically modified cells in which one or more genes have been intentionally "knocked out" or deactivated. Using advanced gene editing technologies like CRISPR-Cas9, we create precise and stable gene disruptions. This allows for a deeper, more accurate understanding of gene function in a controlled setting.

Customizable Knockouts

Tailored to your specific research needs. We can target genes across a wide variety of cell types.

Validated Performance

Each knockout cell line undergoes rigorous quality control and validation to ensure reliable, reproducible results.

Wide Applications

Ideal for functional genomics, disease modeling, drug discovery, and core biomedical research.

Applications of Knockout Cell Lines

Gene Function Research

Knockout cell lines are fundamental for functional genomics. They help you uncover the role of specific genes in cellular processes like growth, differentiation, and metabolism.

Disease Modeling

These cell lines are invaluable for creating accurate in vitro models of diseases, from cancer to neurodegenerative disorders. They allow for better mechanistic understanding and pre-clinical testing of therapeutic strategies.

Drug Discovery & Target Identification

Knockout cell lines are instrumental in high-throughput drug screening. They help researchers identify and validate potential drug targets by assessing compound effects in the absence of a specific gene.

Why Choose Runtogen's KO Cell Lines?

Cutting-edge Technology

We utilize the latest CRISPR-Cas9 gene editing tools to create high-precision knockout cell lines.

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Extensive Ready-Made Library

Save valuable time with immediate access to over 5,000 ready-made, validated knockout cell lines in our catalog.

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Fast Delivery & Expert Support

Get your cell lines quickly and benefit from the support of our specialist team.

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High-Quality Standards

Homozygous clones validated by Sanger sequencing, edited in commonly used cell lines.

Accelerate Your Research

Whether you are studying basic gene function, developing advanced disease models, or screening for new drug targets, our knockout cell lines are engineered to meet the highest standards of quality and precision.

Online Inquiry

  • SOX2 Knockout Cell Line-HEK293

    SOX2 Knockout Cell Line-HEK293

    Catalog#: RK-0107
    Size: 1*10^6 cells/vial
    Gene Name: SOX2
  • USP10 Knockout Cell Line-HEK293

    USP10 Knockout Cell Line-HEK293

    Catalog#: RK-0121
    Size: 1*10^6 cells/vial
    Gene Name: USP10
  • SAMHD1 Knockout Cell Line-HEK293

    SAMHD1 Knockout Cell Line-HEK293

    Catalog#: RK-0123
    Size: 1*10^6 cells/vial
    Gene Name: SAMHD1
  • HILPADA Knockout Cell Line-HCT116

    HILPADA Knockout Cell Line-HCT116

    Catalog#: RK-1279
    Size: 1*10^6 cells/vial
    Gene Name: HILPADA
  • PINK1 Knockout Cell Line-HEK293

    PINK1 Knockout Cell Line-HEK293

    Catalog#: RK-0129
    Size: 1*10^6 cells/vial
    Gene Name: PINK1
  • HELLS Knockout Cell Line-HCT116

    HELLS Knockout Cell Line-HCT116

    Catalog#: RK-1280
    Size: 1*10^6 cells/vial
    Gene Name: HELLS
  • RNF181 Knockout Cell Line-HEK293

    RNF181 Knockout Cell Line-HEK293

    Catalog#: RK-0138
    Size: 1*10^6 cells/vial
    Gene Name: RNF181
  • IGF2BP2 Knockout Cell Line-HEK293

    IGF2BP2 Knockout Cell Line-HEK293

    Catalog#: RK-0004
    Size: 1*10^6 cells/vial
    Gene Name: IGF2BP2
  • EGLN2 Knockout Cell Line-HEK293

    EGLN2 Knockout Cell Line-HEK293

    Catalog#: RK-0139
    Size: 1*10^6 cells/vial
    Gene Name: EGLN2