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Knockout Cell Lines

Knockout (KO) Cell Lines

CRISPR KO Cell Lines for Precise Gene Editing

Runtogen's CRISPR Knockout Cell Lines are powerful, specially engineered tools for researchers. They enable the exploration of gene function and the advancement of biological research. By selectively disrupting specific genes, these cell lines allow you to study the impact of gene loss on cellular processes, disease models, and drug discovery pathways.

What Are Knockout Cell Lines?

Knockout cell lines are genetically modified cells in which one or more genes have been intentionally "knocked out" or deactivated. Using advanced gene editing technologies like CRISPR-Cas9, we create precise and stable gene disruptions. This allows for a deeper, more accurate understanding of gene function in a controlled setting.

Customizable Knockouts

Tailored to your specific research needs. We can target genes across a wide variety of cell types.

Validated Performance

Each knockout cell line undergoes rigorous quality control and validation to ensure reliable, reproducible results.

Wide Applications

Ideal for functional genomics, disease modeling, drug discovery, and core biomedical research.

Applications of Knockout Cell Lines

Gene Function Research

Knockout cell lines are fundamental for functional genomics. They help you uncover the role of specific genes in cellular processes like growth, differentiation, and metabolism.

Disease Modeling

These cell lines are invaluable for creating accurate in vitro models of diseases, from cancer to neurodegenerative disorders. They allow for better mechanistic understanding and pre-clinical testing of therapeutic strategies.

Drug Discovery & Target Identification

Knockout cell lines are instrumental in high-throughput drug screening. They help researchers identify and validate potential drug targets by assessing compound effects in the absence of a specific gene.

Why Choose Runtogen's KO Cell Lines?

Cutting-edge Technology

We utilize the latest CRISPR-Cas9 gene editing tools to create high-precision knockout cell lines.

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Extensive Ready-Made Library

Save valuable time with immediate access to over 5,000 ready-made, validated knockout cell lines in our catalog.

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Fast Delivery & Expert Support

Get your cell lines quickly and benefit from the support of our specialist team.

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High-Quality Standards

Homozygous clones validated by Sanger sequencing, edited in commonly used cell lines.

Accelerate Your Research

Whether you are studying basic gene function, developing advanced disease models, or screening for new drug targets, our knockout cell lines are engineered to meet the highest standards of quality and precision.

Online Inquiry

  • MAT2B Knockout Cell Line-HEK293

    MAT2B Knockout Cell Line-HEK293

    Catalog#: RK-4545
    Size: 1*10^6 cells/vial
    Gene Name: MAT2B
  • TIRAP Knockout Cell Line-HEK293

    TIRAP Knockout Cell Line-HEK293

    Catalog#: RK-4438
    Size: 1*10^6 cells/vial
    Gene Name: TIRAP
  • RUNX1 Knockout Cell Line-HEK293

    RUNX1 Knockout Cell Line-HEK293

    Catalog#: RK-4439
    Size: 1*10^6 cells/vial
    Gene Name: RUNX1
  • MYOM2 Knockout Cell Line-HEK293

    MYOM2 Knockout Cell Line-HEK293

    Catalog#: RK-4443
    Size: 1*10^6 cells/vial
    Gene Name: MYOM2
  • ACVR2A Knockout Cell Line-HEK293

    ACVR2A Knockout Cell Line-HEK293

    Catalog#: RK-4446
    Size: 1*10^6 cells/vial
    Gene Name: ACVR2A
  • ERBIN Knockout Cell Line-HEK293

    ERBIN Knockout Cell Line-HEK293

    Catalog#: RK-4451
    Size: 1*10^6 cells/vial
    Gene Name: ERBIN
  • PSME1 Knockout Cell Line-HEK293

    PSME1 Knockout Cell Line-HEK293

    Catalog#: RK-4455
    Size: 1*10^6 cells/vial
    Gene Name: PSME1
  • TNFAIP3 Knockout Cell Line-HEK293

    TNFAIP3 Knockout Cell Line-HEK293

    Catalog#: RK-4459
    Size: 1*10^6 cells/vial
    Gene Name: TNFAIP3
  • HNRNPA0 Knockout Cell Line-HEK293

    HNRNPA0 Knockout Cell Line-HEK293

    Catalog#: RK-4460
    Size: 1*10^6 cells/vial
    Gene Name: HNRNPA0