Knockout Cell Lines

CRISPR KO Cell Lines for Precise Gene Editing

Runtogen's CRISPR Knockout Cell Lines are specially engineered to provide researchers with powerful tools for exploring gene function and advancing biological research. By selectively disrupting specific genes, these cell lines enable you to study the impact of gene loss on cellular processes, disease models, and drug discovery.

What Are Knockout Cell Lines?

Knockout cell lines are genetically modified cells where one or more genes have been intentionally "knocked out" or deactivated. Using advanced gene editing technologies like CRISPR-Cas9 or RNAi, we create precise and stable gene disruptions, allowing for a deeper understanding of gene function.

Key Features:

• • Customizable Knockouts: Tailored to your research needs, our knockout cell lines can target specific genes across a variety of cell types.

• • Validated Performance: Each knockout cell line undergoes rigorous quality control and validation to ensure reliable and reproducible results.

• Wide Applications: Ideal for functional genomics, disease modeling, drug discovery, and biomedical research.

Applications of Knockout Cell Lines

• • Gene Function Research: Knockout cell lines enable functional genomics studies, helping you uncover the role of specific genes in cellular growth, differentiation, and metabolism.

• • Disease Modeling: These cell lines are invaluable for creating disease models, from cancer to neurodegenerative diseases, allowing for better understanding and testing of therapeutic strategies.

• • Drug Discovery: Knockout cell lines are instrumental in drug screening, helping researchers identify potential drug targets and assess the effects of compounds on specific genes.

Why Choose Our KO Cell Lines?

• • Cutting-edge Technologies: We use the latest gene editing tools like CRISPR-Cas9 to create high-precision knockout cell lines.

• • Fast Delivery: Get your knockout cell lines quickly and start your research with minimal delays.

• • Expert Support: Our team of specialists is available to help you design the best knockout model for your specific research needs.

Runtogen offers an extensive catalog of high-quality ready-made and made-to-order KO cell lines. We have 5,000+ knockout cell lines in stock, generated using CRISPR/Cas9 genome editing technology. Our KO cell lines are edited on the most commonly used cell lines, such as HEKs, HeLa, A549, HCT116, THP-1, HepG2, Huh-7, etc. These ready-made KO cell lines are gene knockout homozygous clones validated by Sanger sequencing. Save time with immediate access to the industry's largest library of immortalized diploid KO cell lines here. 

Whether you're studying gene function, developing disease models, or screening for drug targets, our knockout cell lines are engineered to meet the highest standards of quality and precision.

Ready to accelerate your gene editing research? Contact us today to learn more about our knockout cell lines or get started on your Custom Knockout Cell Line Service project.