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| Description | F-36P is a human cytokine-dependent leukemia cell line derived from a patient with myelodysplastic syndrome (MDS) that progressed to acute myeloid leukemia (AML). The cells require GM-CSF or IL-3 for growth and retain characteristics of hematopoietic progenitor cells. F-36P is widely used for studies of leukemia biology, hematopoietic differentiation, cytokine signaling, and anti-cancer drug screening. |
| Product Name | F-36P Cell Line |
| Cat.No | RWT-1250 |
| Product type | Human acute myeloid leukemia cell line |
| Product category | Tumor Cell Lines |
| Size | 1*10^6 cells/vial |
| Description | F-36P is a human cytokine-dependent leukemia cell line derived from a patient with myelodysplastic syndrome (MDS) that progressed to acute myeloid leukemia (AML). The cells require GM-CSF or IL-3 for growth and retain characteristics of hematopoietic progenitor cells. F-36P is widely used for studies of leukemia biology, hematopoietic differentiation, cytokine signaling, and anti-cancer drug screening. |
| Tissue | Pleural effusion |
| Species | Human |
| Gender | Male, 68-year-old |
| Disease | Acute erythroid leukemia |
| Biosafety Level | BSL 1 |
| Morphology | Lymphoblastoid, Adherent and suspension |
| Passage Ratio | 1:2-1:4 |
| Culture Method | RPMI1640, 20%FBS, 10 ng/ml GM-CSF, 1% P/S |
| Quality Control | STR authenticated & mycoplasma free; ≥90% viability on delivery |
| Shipping | Dry ice |
| Storage | Cryopreserved cells are supplied in liquid nitrogen vapor phase and should be stored immediately in liquid nitrogen upon receipt. For optimal recovery, rapid thawing in a 37°C water bath followed by immediate transfer into pre-warmed complete culture medium is recommended. |
| Warranty | F-36P Cell Line is warranted for 30 days from the date of shipment, provided that the customer has stored and handled the product according to the information included on the product datasheet, website, and COA. |
| Disclaimers | For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
| Applications | F-36P cells are widely used as an in vitro model for studying hematopoietic progenitor cell biology, cytokine-dependent proliferation, and leukemia pathogenesis. Their responsiveness to GM-CSF and IL-3 makes them particularly valuable for investigating cytokine signaling pathways, including JAK/STAT, PI3K/AKT, and MAPK signaling. In addition, F-36P cells are frequently employed in hematopoietic differentiation studies, anti-leukemia drug screening, and functional genomics research, including gene overexpression and CRISPR-mediated genome editing. |
If use of this product results in a scientific publication, it should be cited in the publication as: F-36P Cell Line (Runtogen RWT-1250).
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Inquire the F-36P Cell Line by filling out the form below. We’ll get back to you within 24 hours with a quote.
