A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include: 

Ba/F3

A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity. 

K562

A human myeloid cell line that can be used to identify over- and under-active kinases. 

MOLM13/MV4–11

A human myeloid cell line that can be used to identify over- and under-active kinases. 

HEK293T

A human cell line that can be used to study thymidine kinase 1. 

Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.

Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.